# Origin of Misfolding
> Local Misfolding 
> Vulnerable Sites
> Common Epitopes
> Generic Misfoldon 

# Therapeutics 
> Sequence Analysis
> Designing Conjugate Sequence 
> Aggregation Propensity
> Effective Aggregation Suppressor   

# Diagnosis
> Physicochemical Properties
> Clinical Observables 
> Universal Predictor
> Novel Deleterious and Beneficial Mutants

# LLPS
> Molecular Mechanism
> Sequence- and Length-Dependence  
> Impact of Ionic Strength
> Aggregation vs. Phase Separation

# Novel Structure Prediction
> Going Beyond AlphaFold
> How Good is Conventional MD 
> Replica Exchange - REMD and REST
> Universality of the Approach

# Forcefield Optimization
> Possible Combinations
> Polymer Dynamics
> Conformational Landscape Characterization
> Comparison with Experiments